Fig. 3

Nhlrc2^FINCA/− mice showed no morphological changes, neurodegeneration, or demyelination in the brain. a Upper: Representative image of 32-week-old female Nhlrc2^FINCA/− and Nhlrc2^+/+ hippocampal section stained with Luxol fast blue. Lower: a higher magnification showed no neurodegeneration in the dorsal hippocampus. b Upper: Representative image of 32-week-old male Nhlrc2^FINCA/− and Nhlrc2^+/+ cerebella. Lower: Higher magnification of the area inside the red box showing normal granule and Purkinje cells (black arrow). c Dot blots showing brain weight after fixation; area of the hippocampal section and thickness of corpus callosum measured from the midline. Individual datapoints, means and SEM are shown. There were no significant changes (Student’s t-test)